Stat4 antibody
Web"STAT4 antibodies" comparison At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As such, we are comparing our antibodies with other vendors, enabling easy identification and comparisons of key data to help you choose the suitable antibody for your needs. WebSTAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
Stat4 antibody
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WebSTAT4 has a cytoplasmic localization and is translocated into the nucleus in response to activation by JAK, which phosphorylates STAT4 at a tyrosine residue. Various ligands, including interferons and growth factors, induce activation of the JAK kinases, which induce STAT activation. WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information …
WebHuman STAT4 is 748 amino acids (aa) in length. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo- or heterodimerizes with other STAT proteins, which then translocate to the nucleus and … WebSystemic scleroderma. A normal variation in the STAT4 gene has been associated with an increased risk of developing systemic scleroderma, which is an autoimmune disorder characterized by the buildup of scar tissue (fibrosis) in the skin and internal organs. …
WebHuman/Mouse STAT4 Antibody Summary Species Reactivity Human, Mouse Specificity Detects human and mouse STAT4. No cross-reactivity with the other STATs has been detected by immunoprecipitation or by Western blotting. Source Polyclonal Goat IgG Purification Antigen Affinity-purified Immunogen Mouse STAT4 synthetic peptide aa 675 … WebOur results were contradicted with Yang et al, the STAT4 rs7574865 variant was linked to positive anti-dsDNA antibodies 36 and Kadota et al, the rs7574865 T allele in the STAT4 gene was linked to cutaneous manifestation such as malar rash in SLE patients. 37 Furthermore, the rs3747517 “CT+TT” genotype was linked to SLE protection, while the ...
WebThe antibody is expected to exhibit the same species cross-reactivity as the unconjugated Phospho-Stat4 (Tyr693) (D2E4) Rabbit mAb #4134. Product Usage Information Storage Supplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/ml BSA. Store at 4°C. Do not aliquot the antibodies. Protect from light. Do not freeze. Protocol
WebSTAT4 Recombinant Rabbit Monoclonal Antibody (2H9L5) Advanced Verification This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. View all (60) STAT4 antibodies Add To Cart Datasheet Protocols Questions & Answers Tech Support Antibody Testing Data (8) Advanced Verification (1) Application … tacoholics laceyWebHowever, STAT4 phosphorylation results must be interpreted with caution due to the lack of a proper STAT4 antibody to assess total STAT4 expression by flow cytometry. For this reason, STAT4 is meant to help only in the diagnosis of other forms of MSMD. ... STAT4 encodes the signal transducer and activator of transcription 4 protein (STAT4), ... tacojohnscom lawrence ksWebSee all STAT4 primary antibodies Description Rabbit polyclonal to STAT4 (phospho Y693) Host species Rabbit Tested applications Suitable for: IP, WB, IHC-P, ELISA more details Species reactivity Reacts with: Mouse, Human Immunogen Synthetic peptide … tacoholic forked river njWebHuman/Mouse STAT4 Antibody Summary Species Reactivity Human, Mouse Specificity Detects human and mouse STAT4. No cross-reactivity with the other STATs has been detected by immunoprecipitation or by Western blotting. Source Polyclonal Goat IgG … tacoflowWebAug 17, 2024 · Stat4 Antibody (C-4) is a mouse monoclonal IgG 2b κ Stat4 antibody, cited in 7 publications, provided at 200 µg/ml specific for an epitope mapping between amino acids 10-31 at the N-terminus of Stat4 of mouse origin tacol lindsborg ks hoursWebImmunogen. Synthetic peptide corresponding to human STAT4 phosphorylated at tyrosine 693. Formulation. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) Preparation. The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. tacoland gameWebThe leucocytes were washed, permeabilized with BD Phosflow™ Perm Buffer III (Cat. No. 558050) on ice for 30 minutes, washed, and then stained with BD Phosflow™R718 Mouse Anti-Stat4 (pY693) antibody (Cat. No.567631). The fluorescence histograms showing Stat4 (pY693) expression were derived from events with the forward and side light-scatter ... tacol thrift shop lindsborg ks